The invention discloses a cleaning control method of a cleaning machine. The cleaning control method of the cleaning machine is characterized by comprising steps of setting a first organic matter sensor for detecting an organic matter content in inlet water in an water inlet system of the cleaning machine, setting a second organic matter sensor for detecting an organic matter content in drainage water in a drainage water system of the cleaning machine, starting the first organic matter sensor to detect the organic matter content in inlet water at least when a second cleaning subprogram is executed, starting a second organic matter sensor to detect the organic matter content in the drainage water when the second cleaning sub-program is completed, if a numerical value obtained through dividing a difference value between the organic matter contents of the drainage water and the inlet water by the organic matter content of the inlet water is smaller than 5%, determining that an cleaned object is clean, and directly executing a rinsing program instead of executing a follow-up cleaning sub-program. Compared with the prior art, the cleaning control method of cleaning machine can dynamically regulate the cleaning time according to the contamination condition f the cleaned object.