The application discloses a vortex flow cleaning system suitable for a defecation nursing device, comprising a urine and feces collector, a water supply system and a negative-pressure sewage pumping system, wherein one end of the urine and feces collector is provided with an opening and the other end is provided with an outlet, a urine and feces collecting cavity is arranged between the opening and the outlet; the urine and feces collecting cavity gradually becomes smaller along the direction from the opening to the outlet, and the cavity wall of the urine and feces collecting cavity is a smooth hook face; the urine and feces collector is also provided with an air inlet hole and a water inlet hole which are both communicated with the urine and feces collecting cavity, the air inlet hole and the water inlet hole are arranged along a tangential direction of the cavity wall of the urine and feces collecting cavity; the water supply system is connected with the water inlet hole; the negative-pressure sewage pumping system is connected with the outlet. According to the vortex flow cleaning system suitable for the defecation nursing device, the air inlet hole and the water inlet hole are arranged in the urine and feces collector along the tangential direction of the urine and feces collecting cavity, so that the water and air entering from the tangential direction can form a spiral vortex flow along the inner wall of the urine and feces collecting cavity, the cleaning range of the vortex flow is wide and the effect is good, the urine and feces collecting cavity is omnidirectionally cleaned while the urine and feces are flushed away; the water is saved, and no high pressure water pump is needed to drive a water source to enter, so that the cost is reduced.