Disclosed is an on-satellite configuration layout determining method of multi-field-of-view star sensors. Firstly, all possible optical axis orientations of the three star sensors are traversed according to a satellite Pro/E three-dimensional model, and then feasible solution sets which meet the requirement of a star stray radiation suppression angle of the star sensors are obtained; then feasible solution sets meeting the requirements of a sunlight suppression angle and a geogas light suppression angle at a zero attitude are obtained according to the feasible solution sets meeting the requirement of the star stray radiation suppression angle of the star sensors; and finally feasible solution sets meeting the requirements of the sunlight suppression angle and the geogas light suppression angle at a non-zero attitude are figured out, and therefore ultimate on-satellite configuration layout orientations of the multi-field-of-view star sensors are finished. Compared with the prior art, the method has the engineering practicability, is better than manual experience trial assembly in directivity and effectiveness and is excellent in practical effect.