The invention relates to a suture end cyclization method. A multi-stand suture is adopted, and the method includes the steps that firstly, a point close to a free end of the suture is selected and marked as a first stretching-out point, and the free end stretches out from the first stretching-out point to form a suture ring; then, a point, relatively close to the free end, on the suture ring is selected and marked as a second stretching-out point, the first stretching-out point and the second stretching-out point are located on the portions, at the two ends of the suture ring, of the suture respectively, and the free end is stretched out from the second stretching-out point; then, the suture is tightened up, so that the first stretching-out point coincides with the second stretching-out point; finally, two free ends of the suture form a new free end by threading. The suture end cyclization method is easy to operate and firm in fixation, the working efficiency of operators is greatly improved, the suture can be reused, and the method is economical and environmentally friendly.