The embodiment of the invention provides a processing method of a microreactor and the microreactor. The processing method of the microreactor comprises the following steps: processing a sapphire crystal blank into a microreactor substrate; processing a microreaction channel on the surface of the microreactor substrate; forming a microreaction unit by the reactor substrates connected in a laminated manner; and packaging the connecting faces of the microreaction units. A sapphire substrate produced by the processing method of the microreactor provided by the invention is formed to a microreactor production nano material. In the reaction process, the material is reacted in a nanoscale microchannel, the process conditions are controlled well, and the nanomaterial is easily obtained. The product is good in quality, the cost is low and the efficiency is high.