The invention relates to the field of medicines, and mainly relates to a novel crystal form of cefotiam hydrochloride and a preparation method. The cefotiam hydrochloride compound is measured by using Cu-Ka rays, and main characteristic peaks are displayed at places that 2theta is 10.981 degrees, 14.959 degrees, 18.320 degrees, 19.141 degrees, 19.399 degrees, 23.121 degrees and 27.440 degrees in an obtained X-ray powder diffraction pattern. The cefotiam hydrochloride prepared by using the method is high in sample purity, good in stability, low in moisture, low in organic solvent residue, uniform in size distribution, good in flowability and applicable to sub-packaging. The preparation method provided by the invention is high in process yield, simple and convenient and easy to control, low in preparation cost and safe and reliable.