The invention discloses a wind power generation device with vertical blades. The wind power generation device comprises a power wheel, the power wheel is horizontally arranged on a base, a plurality of supporting grooves of the blades are formed in the upper end surface of the power wheel, one vertical blade is arranged on each supporting groove, a connecting wheel is arranged at the upper end of each blade, an electric generator is arranged on the periphery of the power wheel, a transmission component is arranged on a space between a spindle of the electric generator and the periphery of the power wheel, a wind power signal acquirer is arranged near the electric generator and connected with a controller through a cable or a wireless communication module, and the rotating speed of the power wheel is controlled by the controller and a brake connected with the power wheel. The wind power generation device has the advantages that the wind power generation device is relatively simple in structure, safe and reliable to run, convenient and rapid to use, high in electric generating efficiency and low in cost, can be installed and used at the densely populated place and the like.