The present invention discloses a method and system for network reconfiguration in an urban distribution network. The method comprises: establishing multi-objective optimization functions of annual power shortage of the system, average power-off duration of the system, average power-off frequency of the system and minimal network loss of the urban distribution network; determining constraint conditions of the multi-objective optimization functions and the weight of each objective optimization function; setting an on-off initial value of the switch of each load node in the urban distribution network; according to the on-off initial value of the switch of each load node, the multi-objective optimization functions and the constraint conditions, using the multi-objective particle swarm optimization algorithm based on the decomposition and differential evolution to solve the multi-objective optimization functions; and according to the on and off of the switch of each load node in the urban distribution network corresponding to the weighted and minimum multi-objective optimization function solution, reconstructing the network in the urban distribution network. According to the method and system disclosed by the present invention, the network loss of the urban distribution network containing the distributed power supply and the automobile charging station can be optimized, the operation cost can be reduced, and the supply voltage quality of the urban distribution network can be improved at the same time.