The invention discloses a portable anti-fake color printing packing box, and solves the problems of bad physical strength and anti-fake effect and troublesome obtaining of anti-fake results in the prior art. The packing box is formed by folding and bonding a stone paperboard; a colorful pattern surface layer and a single-color inner layer are respectively printed on the front and reverse surfaces of the stone paperboard; a transparent waterproof and dustproof film is hot pressed on the colorful pattern surface layer; the stone paperboard comprises a stone paperboard body and a coating layer; a transparent window is formed in a box body of the packing box; a NFC label and a two-dimensional code tracing pattern coated with a transparent waterproof layer on the surface are arranged on the back surface of the box body of the packing box; and a micro liquid crystal display screen, a microprocessor and a micro wireless transceiver are embedded in the side surface of the box body of the packing box. The packing box is simple in structure and convenient in use, can effectively prevent water, fog, oil and insects, is high in physical strength, beautiful in appearance, high in anti-fake performance and convenient in obtaining path of the anti-fake results, achieves internal product identifying function, and greatly widens the application range.