The invention discloses a pipeline support with a built-in comb-shaped anti-vibration pad. The pipeline support comprises bolts, a pipe clamp, the anti-vibration pad and a support base. The upper portion of the support base is a semi-circular ring, and extending-out lugs at the two ends of the semi-circular ring are provided with through holes. The pipe clamp is also a semi-circular ring, the pipe clamp is matched with the support base to form a circular clamp which is connected by the bolts, and an annular boss is arranged on the inner wall of the circular clamp. The anti-vibration pad is arranged in the circular clamp which is formed by the pipe clamp and the support base in a matched manner, equilong radial opening grooves are evenly distributed in the bent inner hole wall of the anti-vibration pad to form comb teeth, and a groove formed in the outer wall and the annular boss which is on the inner wall of the pipe clamp and the inner wall of the support base are matched to from an axial positioning structure. According to the pipeline support with the built-in comb-shaped anti-vibration pad, the anti-vibration pad is additionally provided with the comb teeth, although the structure is very simple, the bending performance of the anti-vibration pad is effectively improved, and the vibration attenuating effect, the heat isolation effect and the sound absorbing effect of the whole support are remarkably improved. Therefore, the pipeline support with the built-in comb-shaped anti-vibration pad is especially suitable for being matched with ships and warships.