The embodiment of the invention discloses a double hole casting technology of a pressure membrane assembly. The process comprises the following steps: mounting a packaging assembly on a to-be-assembled end of the pressure membrane assembly; casting a first colloid through a first casting pipe to form a first packaging layer extending from a cavity bottom of a casting end cover to a membrane shell; after the first packaging layer is cured, casting a second colloid through a second casting pipe to form a second packaging layer extending from the first packaging layer to the membrane shell; and after the second packaging layer is cured, taking down the packaging assembly, excising the packaged membrane thread along the end surface of the to-be-assembled end of the membrane shell to package the to-be-assemble end of the pressure membrane assembly. By applying the packaging process provided by the embodiment of the invention, the first packaging layer and the second packaging layer can be casted separately, and all first packaging layer and part of second packaging layer are excised, so that packaging is finished. In the packaging process, the membrane thread holes are not needed to be manually blocked, and generation of waste threads can be also reduced.