The invention discloses a method for improving the stability and the durability of leather on the basis of nanometer titanium dioxide. The method comprises the following steps: by adoptingcoupling-agent method, with alcohol solvent of tetraethoxysilane, nanometer titanium dioxide and low-viscosity urea resin as materials, introducing an organic functional film for titanium dioxide, inducing a super-hydrophilic effect by light generated by photogenerated holes on the surface of the titanium dioxide and forming a super-hydrophilic film on the surface of the leather. The method disclosed by the invention has the advantages that the weather resistance, the antibacterial property and the self cleaning property of the surface of the leather can be enhanced.