The invention discloses an automatic testing system and method for an SDNS (Secure Domain Name Server) interface. The system comprises a main process control module, a service monitoring module, an expected result module and a report generation module, wherein the main process control module is used for reading a testing configuration file, obtaining the description file of an interface test case of the SDNS interface to be tested on the basis of the test configuration file and the appointed path of interface testing data, calling and obtaining a practical calling result on the basis of the description file of the interface test case and the interface testing data under the appointed path, and emitting an instruction; the service monitoring module is used for emitting service monitoring according to a service monitoring instruction emitted from the main process control module to obtain and store service monitoring result data; the expected result module is used for comparing the practical calling result with the expected calling result to obtain an automatic testing result; and the report generation module is used for generating a test report according to a report generation instruction emitted from the main flow control module on the basis of the automatic test result. The testing system can be quickly implemented and is high in universality.