The invention discloses an efficient sewage purification device, which comprises a physicochemical treatment box, a biological treatment box, a water inlet, a dosing port, a filter unit, an aerobic tank and an anoxic tank. The left side of the upper part of the physicochemical treatment box is provided with the water inlet. The middle part of the right side of the physicochemical treatment box is provided with a pipeline, which is communicated with the physicochemical treatment box and the biological treatment box. The middle position of the pipeline is equipped with a sewage valve. A baffle plate 1 and a baffle plate 2 are arranged inside the physicochemical treatment box. The baffle plate 1 and the baffle plate 2 divide the physicochemical treatment box into three treatment areas, which are successively a first treatment area, a second treatment area and a third treatment area from the left to the right. Meanwhile, the upper part of the baffle plate 1 is provided with an opening 1, and the upper part of the baffle plate 2 is provided with an opening 2. The upper part of the first treatment area is provided with the dosing port, which is arranged at the right side of the water inlet. The device of the invention has a simple structure, is convenient to use and has a good water purification effect. After purification, water quality is stable.