The invention provides an oriented strand board and thin laminated wood combined new structure composite door making method. The method comprises the following steps that an oriented strand board plain board is subjected to thickness controlling and sanding, wherein thickness controlling and sanding are conducted on the surface of the oriented strand board plain board needing to be used through a sander; oriented strand board sizing is conducted, wherein an oriented strand board obtained after sanding is conducted is subjected to sizing machining through a double-sided panel sizing machine and the like; solid wood stile, upper stile and lower stile cutting is conducted, wherein solid wood side stiles, an upper stile and a lower stile are cut to be the side stiles, the upper stile and the lower stile which have the required specifications according to the technological requirements and dimensions, the side stiles, the upper stile and the lower stile are subjected to finish machining, burrs on edge strips are removed through a four-side moulder, the edge strip surfaces are made smooth, and meanwhile the edge strips are cut to make the dimensions of the edge strips more accurate; the oriented strand board is combined with the solid wood side stiles, the upper stile and the lower stile, the oriented strand board is embedded into a door stile, and the oriented strand board and the door stile are fixed. The composite door has the advantages of being stable in structure, simple in machining technology, capable of saving raw materials and beneficial to energy conservation and environment friendliness.