The invention relates to the technical field of microorganism, and aims at providing bacillus methylotrophicus H0 with high yield of oligopeptides in a fermentation product and application of the strain in producing feather oligopeptide powder by degrading feathers. The preservation number of the bacillus methylotrophicus H0 is CGMCC (China General Microbiological Culture Collection Center) No. 14263. The technical scheme adopted by the invention is characterized in that the bacillus methylotrophicus H0 is subjected to activation culture to obtain first-stage seed liquid, then the first-stage seed liquid is inoculated into a beef extract-peptone medium to be cultured to obtain second-stage seed liquid; the second-stage seed liquid is inoculated into a fermentation medium to be cultured to obtain a fermentation product which can be used for preparing the feather oligopeptide powder or an oligopeptide solution. The bacillus methylotrophicus H0 has the advantages that an intact feather can be almost completely degraded, the yield of the feather oligopeptide in a degradation product is high, and the bacillus methylotrophicus H0 can be used for producing the feather oligopeptide powder with high digestibility and high additional value.