The invention discloses a data security transmission method based on a message queue, and relates to the field of data security application in the field of information and communication technologies. In order to ensure data security, an electric power company deploys a strong isolating device of the state grid between internal and external networks, which is mainly suitable for the transmission of small data, the transmission efficiency of large files is low, and the real-time communication response time is long. The data security transmission method of the invention includes a method for transmitting data from an external network to an internal network and a method for transmitting data from an internal network to an external network. In the technical scheme, an original strong isolating device gateway is replaced with a forward and reverse gateway device and the message management of the forward and reverse gateway device is realized by ToprowMQ, so as to allow the access of external network services to internal network applications and the access of the internal network applications to the external network services to facilitate data sharing; and furthermore, MQ pre-message services and MQ message management services are added for the internal and external networks for message communication with the MQ gateway, the efficiency is improved, the normal operation of all existing application systems are ensured, the efficiency and quality of the internal and external network penetration are improved, and the data transmission efficiency and response speed are increased.