The invention discloses a traditional Chinese medicine nanometer decoction piece for relieving constipation and a preparation method thereof. The traditional Chinese medicine nanometer decoction piece is prepared from the following ingredients in parts by weight: 10 to 12 parts of cortex magnoliae officinalis, 10 to 12 parts of lotus stamen, 6 to 7 parts of fructus tsaoko, 10 to 12 parts of radix angelicae sinensis, 8 to 9 parts of herba cistanche, 13 to 15 parts of rhizoma anemarrhenae, 13 to 15 parts of radix scutellariae, 15 to 17 parts of rhizoma bletillae, 15 to 17 parts of Chinese honeylocust fruits, 15 to 17 parts of herba dendrobii, 10 to 12 parts of liquorice roots, 20 to 23 parts of mulberries, 20 to 23 parts of pollen, 20 to 23 parts of dwarf lilyturf roots, 200 to 230 parts of rice vinegar, 300 to 350 parts of rhizoma dioscoreae powder, 50 to 60 parts of fish skin collagen and 100 to 120 parts of yellow wine. The traditional Chinese medicine nanometer decoction piece provided by the invention has the advantages that the nanometer decoction piece is light; the administration is convenient; the medicine effect is stable; the contained beneficial ingredients have the health care effects of nourishing yin, tonifying the spleen, resisting the inflammation, enhancing the immunity and the like; no toxic and side effects exist; the decoction piece can be taken for a long time; the nourishing and prevention effects are achieved on people with body weakness; the symptoms such as constipation can be relieved.