The invention relates to a motor vehicle driving permission device based on artificial intelligence. The motor vehicle driving permission device comprises a pressure sensor, a microphone, a camera, an intelligent voice conversation system, a liquid crystal display with a touch function and a microprocessor, wherein the intelligent voice conversation system is used for transferring pre-stored voice fragments for broadcasting; the interactive reply content of a driver and the voice fragments is acquired through utilizing a microphone, or the driver can also choose to answer questions on the liquid crystal display with the touch function; the facial expression of the driver is acquired by the camera; and based on the reply content and the facial expression of the driver, the situation whether the emotion of the driver is stable or not is judged, and if the emotion of the driver is not stable, a signal of refusing ignition is outputted by the microprocessor to an ignition controller, so that the current motor vehicle cannot normally ignite. According to the motor vehicle driving permission device disclosed by the invention, a facial expression recognition system is arranged in the motor vehicle, so that whether the driver can be permitted to drive the vehicle is judged according to the expression of the driver, and the occurrence of unsafe accidents caused by abnormal emotion of the driver is avoided.