The invention relates to a thermal-resistant and cold-resistant vehicle-mounted video line and a preparation method thereof. The thermal-resistant and cold-resistant vehicle-mounted video line sequentially comprises a conductive core layer, an insulation layer, a shielding layer and a protection layer from inside to outside, wherein the material of the insulation layer is physical foamed polyethylene, the material of the shielding layer is polyester copper foil belt and tin-plated flexible copper line, and the material of the protection layer is polyvinyl chloride. The thermal-resistant and cold-resistant vehicle-mounted video line also has excellent performance of high-temperature resistance, corrosion resistance, oil resistance, vibration resistance, friction resistance, cold resistance, flame retardance and the like except for favorable shielding performance and transmission performance; and moreover, the thermal-resistant and cold-resistant vehicle-mounted video line also has relatively good mechanical property and stable chemical property and has a good commercial prospect.