The invention provides an antenna switching method and a mobile terminal. The method comprises the following steps: determining a call mode of the mobile terminal when receiving a call instruction; acquiring the current call channel corresponding to the call instruction; acquiring an upper antenna weighted value and a lower antenna weighted value corresponding to the current call channel under the call mode of the mobile terminal; determining an optimal antenna according to the upper antenna weighted value and the lower antenna weighted value; and switching to the optimal antenna to perform the call transmission until this call is finished. Therefore, a problem that the call quality and the data transmission quality are lowered since the back-forth switching between the upper antenna and the lower antenna is caused when the signal intensities of the upper antenna and the lower antenna are equivalent can be solved, and the call quality and the data transmission quality can be improved.