The invention relates to a centralized control multi-path DC constant-current source. The centralized control multi-path DC constant-current source comprises a master control board and multiple groups of constant-current sources, wherein each group of constant-current sources comprise ten constant-current circuits, one of the constant-current circuit has a relay function and can be used for receiving a setting parameter and control information of the master control board, sending the setting parameter and the control information to the remaining nine constant-current circuits, acquiring states of the constant-current circuit and the remaining nine constant-current circuits and uploading a real-time current to the master control board, the master control board comprises a master control board micro control unit (MCU), the master control board MCU is connected with a master control board liquid crystal display (LCD), a master control board keyboard, a master control board RS485 interface I and a master control board RS485 interface II, and the master control board RS485 interface II is connected with the constant-current circuit having the relay function in each group of constant-current circuits. The centralized control multi-path DC constant-current source is simple in structure and high in control accuracy, and is convenient to operate, multi-path constant-current source control can be achieved, the master control board can be used for controlling the multiple groups of constant-current sources, completing setting of running states and parameters of each group of constant-current sources and acquiring and displaying a real-time state and a current of each group of constant-current source, and the centralized control multi-path DC constant-current source is high in working efficiency.