The invention discloses a full-automatic bookbinding machine. The full-automatic bookbinding machine comprises a box body, and a page clamping device, a sealing glue device, a sealing face clamping device and a tailoring device are sequentially arranged in the box body from top to bottom. In the whole bookbinding process, page and a cover are manually put in, the work intensity of a bookbinding person is greatly reduced, meanwhile, the bookbinding efficiency is greatly improved, and the machine is suitable for page binding.