The invention discloses a mouse used for palm massage. The mouse comprises a mouse body and a massage band arranged on the lower part of the upper end surface of the mouse body, wherein the massage band is provided with a plurality of convex bodies; one side of the mouse body is provided with a regulation knob; one side of the regulation knob is provided with a button; the middle of the upper end surface of the mouse body is provided with a control button; and the front end surface of the mouse body is provided with an interface, and a control signal is sent to equipment through the interface. After the plurality of convex bodies on the massage band are in contact with a palm position, the acupuncture points and the blood vessels of the palm position can be simulated, so that vessel flowing is quickened, and meridians and collaterals are dredged; and in addition, the knob is regulated to control vibration frequency so as to regulate speed, the control knob is used for controlling dynamics, the design is very convenient for users to regulate massage dynamics and speed according to a situation, and the massage of the user is under an own controllable state. Through the button, the massage band is controlled to be started and stopped, and a misoperation is avoided during use.