The invention discloses a portable universal edge tool box, and relates to the technical field of a medical treatment apparatus. The portable universal edge tool box comprises a box body and a box cover arranged on the upper part of the box body; the box body comprises a holding cylinder with an opening at the upper part and a pin separating device at the upper part of the holding cylinder; the pin separating device comprises a top plate, an encircling plate at the edge of the bottom face of the top plate, a supporting plate arranged in the middle part of the encircling plate, and a pin shearing unit and a pin unloading unit which are located at both sides of the supporting plate; the top plate is provided with pin inlets corresponding to the pin shearing unit and the pin unloading unit. Compared with the prior art, the portable universal edge tool box is safe in use and high in pin separating efficiency.