The invention provides a CUSE (character device in userspace)-based trusted cryptography module simulation system and method. The system comprises a trusted resource management module, a trusted cryptography logic module and a trusted character device operating module. The method includes: adopting a CUSE frame for realizing the trusted resource management module and generating a trusted resourcemanagement interface; 2, adopting the CUSE frame for simulating the trusted cryptography logic module and generating a trusted cryptography logic interface; 3, allowing an upper application to operatea trusted character device through the trusted character device operating module; 4, enabling the trusted character device operating module to call the trusted resource management module to initialize trusted resources; 5, enabling the trusted character device operating module to call the trusted cryptography logic module to execute trusted cryptography logics.