The invention discloses a hand-held plasma jet flow device. The jet flow device comprises an insulating shell, the insulating shell is internally provided with a jet flow unit, a dielectric barrier discharging unit and a charging module for providing power for the jet flow unit and the dielectric barrier discharging unit, the charging module comprises a detachable lithium battery and a charging interface, the jet flow unit introduces airflow into the insulating shell, a discharging region of the dielectric barrier discharging unit generates plasma, and the jet flow unit not only continuously transports the airflow to the discharging area, but also can cool the plasma generated by the discharging area. According to the jet flow device, the detachable lithium battery is arranged in the jet flow device and provides current for the jet flow unit and the dielectric barrier discharging unit, and without an external power supply, the device is convenient to carry and use and can serve as small portable emergency equipment for home or outdoor activities.