The invention discloses a multifunctional trans-radial PCI (percutaneous coronary intervention) postoperative limb blood vessel protection safety belt, and relates to the field of medical instruments.The safety belt comprises a wound pressurizing portion and an adhesive portion, an elastic band is connected between the wound pressurizing portion and the adhesive portion, an ice bag storage sleeveand a gauze filling bag are arranged on the pressurizing surface of the wound pressurizing portion, the ice bag storage sleeve is used for placing an ice bag, the gauze filling bag is filled with gauze rolls, a pressurizing portion connector is arranged at the bottom of the wound pressurizing portion, an adhesive portion connector is arranged at the top of the adhesive portion, and an integral color of a mark belt is red. The safety belt can solve the problems that a postoperative warning sign for a radial operative limb is absent, misoperation is caused, conditions of the operative limb areinconveniently observed in auxiliary nursing, and treatment cost is high due to waste of elastic bandage in the prior art.