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发明公开
CN107596363A 一种鳗弧菌三价灭活疫苗及其应用 无效 - 驳回

一种鳗弧菌三价灭活疫苗及其应用
摘要：
本发明从我国海水养殖鱼类中分离得到三株O1(VAM003)，O2(VAM007)和O3(SMP3)血清型鳗弧菌(Vibrio anguillarum)，菌株VAM003保藏于中国普通微生物菌种保藏管理中心,保藏日期2012年12月7日，保藏编号CGMCC No.6942；菌株VAM003保藏于中国普通微生物菌种保藏管理中心,保藏日期2012年12月7日，保藏编号CGMCC No.6944；SMP3保藏于中国典型培养物保藏中心，保藏日期2016年5月16日，保藏编号CCTCC No.M 2016261。采用该三株鳗弧菌制成三价灭活疫苗，免疫一次就可抵抗多种致病血清型鳗弧菌，大大简化疫苗接种工作量且减少疫苗接种对鱼造成的应激或机械损伤。
摘要（英）：

The invention discloses three strains of vibrio anguillarum including 01(VAM003), 02(VAM007) and 03(SMP3) serotype vibrio anguillarum separated from marine cultured fishes in China, wherein the strainVAM003 is preserved in CGMCC (China General Microbiological Culture Collection Center) with preservation number being CGMCC No.6942 on December 7th, 2012; the strain VAM007 is preserved in CGMCC withpreservation number being CGMCC No.6944 on December 7th, 2012; SMP3 is preserved in CGMCC with preservation number being CGMCC No.M 2016261 on May 16th, 2016. A trivalent inactivated vaccine is prepared from the three strains of vibrio anguillarum, multiple kinds of pathogenic serotype vibrio anguillarum can be resistant after one-time immunization, so that vaccination workload is greatly simplified, and stress or mechanical damage to the fishes due to vaccination is reduced.

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