The invention discloses an acceleration compensation control system of a lifter. The lifter comprises a carrier for carrying carried articles. The lifter is characterized in that a movable base plateis arranged in the carrier, used for supporting the carried articles and can slide upwards or downwards relative to the carrier. The acceleration compensation control system of the lifter comprises adetection module and a control module. The detection module is electrically connected with the control module and used for detecting the amount and the direction of acceleration of the carrier, the control module has control over the actions of the movable base plate according to the detection values of the detection module so that the movable base plate can generate the reverse acceleration in the reverse direction of the carrier synchronously along with the carrier. According to the acceleration compensation control system of the lifter, because of the adopted structure, the amount of acceleration of the blood, relative to the body, in the body of a passenger can be reduced at the moment of starting or braking of the lifter, the comfort level of a passenger when taking the lifter is effectively raised, and more space is made for increasing the speed of the lifter.