The invention relates to a preparation method and an application of a cyanoacrylate derivative (I) containing a tetrazole group. The cyanoacrylate derivative (I) containing the tetrazole group is obtained through reacting 4-(1H-1,2,3,4-tetrazole-1-yl)benzylamine with substituted 2-cyan-3,3-dimethylthioacrylate. The cyanoacrylate derivative containing the tetrazole group has a good prevention and control effect on broadleaf weeds, and can be used for preparing herbicides in the fields of agriculture and gardening.