The invention discloses a cotton and cotton core-spun yarn interwoven elastic-weft adhesive-bonded interlining and a production method thereof. The main production process comprises the steps of overturning seaming, singeing, enzyme-peroxide one-bath scouring bleaching, (repeated bleaching), dyeing, anti-shrinkage finishing, powder point coating, mechanical pre-shrinkage and inspection and packaging. The product has elasticity in the weft direction, the size change rate of water washing in the weft and warp directions is -1.0%-+0.5%, the content of free and hydrolyzed formaldehyde is smaller than or equal to 35 mg/kg, the peeling strength is larger than or equal to 12 N, and the appearance change level of a combined sample after water washing is larger than or equal to 4. The production process design is scientific and reasonable, and the production method is easy to operate.