The invention discloses packaging structure and a display device. The packaging structure comprises two substrates which are opposite to each other; a display element located between the two substrates; a first sealing frame which is formed at the periphery of the display element, wherein the first sealing frame is made of a material which has a drying function and can be sintered with the substrates. A joint sintering layer of a water and oxygen blocking dense structure is formed at the joint of the first sealing frame and the two substrates through sintering. One side, facing outwards, of the first sealing frame is sintered to form an outer sintering layer of the water and oxygen blocking dense structure. The display device comprises the above packaging structure. According to the invention, compared with the prior art, the structure solves a technical problem of lower production efficiency caused by a conventional complex packaging structure.