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发明公开
CN107619384A 苯并杂环衍生物、其制备方法及其在医药上的应用 有权 转让

苯并杂环衍生物、其制备方法及其在医药上的应用
摘要：
本发明涉及苯并杂环衍生物、其制备方法及其在医药上的应用。特别地，本发明涉及一类如通式(I)所示的化合物，该类化合物具有抗肿瘤的用途，抑制血管生成的作用以及作为HIF-1α抑制剂在医学上的应用。其中通式(I)中的各取代基与说明书中的定义相同。
摘要（英）：

The invention relates to a benzo-heterocycle derivative, a preparation method thereof and application of the benzo-heterocycle derivative in medicine, in particular to a compound as shown by general formula (I) that is shown in the description; the compound is applicable to tumor resistance, has the effect of inhibiting vessel generation and is applicable as HIF-1 alpha inhibitor in medicine. In the general formula (I), the substituents are defined the same as those in the description.

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