An acquisition abnormity diagnosis method adopting an acquisition, operation and maintenance knowledge base relates to the field of electricity information acquisition, operation and maintenance. Acquisition abnormity in all fields is always analyzed and judged on the dependence on personal experience at present, so the processing speed is affected, and manpower and material resources are wasted.The method comprises the following steps: 1) analyzing the running state of every terminal and every electricity meter, and qualitatively judging whether the terminals and the electricity meters run normally or not; 2) carrying out knowledge base matching on abnormalities, and listing all abnormal phenomena; 3) querying a matching diagnosis process in a diagnosis database according to the abnormalphenomena, and diagnosing the abnormal phenomena; 4) carrying out the abnormality processing on unfavorable diagnosis results according to the diagnosis results; 5) monitoring the abnormality recovery situation; and 6) storing knowledge in the database when the abnormalities are recovered. The method reduces the workload of fault analysis and solving method finding of operation and maintenance personnel, and avoids manpower and material resource wastes caused by wrong operation and maintenance methods.