The invention relates to chanterelle micromolecular peptide compound wine and a preparation method thereof, which belongs to the technical field of liquid processing, and provides novel wine to the market. The chanterelle micromolecular peptide compound wine is prepared from morchella vulgaris peptide powder, hylocereus undatus peptide powder, lucid ganoderma peptide powder, chanterelle peptide powder, tricholoma matsutake peptide powder, ginseng peptide powder, russule peptide powder, chestnut mushroom peptide powder, coix seed peptide powder, mellea armillaria sporophore peptide powder, purple sweet potato crystal peptide powder and kiwi fruit peptide powder. The peptide powder has an efficacy for beautifying the skin and is adopted as main materials. Polysaccharide, vitamins, trace elements, essential oil and the like are then adopted as auxiliary materials. The main materials and the auxiliary materials are weighed, mixed according to different ratios, dried and packed to obtain mixed peptide powder. The mixed peptide powder is then mixed with stock liquor according to a ratio of 1 to 50 to prepare the peptide wine. The chanterelle micromolecular peptide compound wine has an efficacy for supplementing the nutrition.