The invention belongs to the technical field of chemical adhesives, and particularly relates to an ultraviolet light resistant and high-low temperature resistant silicone adhesive and a preparation method thereof. The silicone adhesive comprises, by weight, 10-20 parts of epoxy resin compounds, 20-60 parts of 400-2000cps end vinyl ethyl phenyl polysiloxane, 15-40 parts of end group hydrogen polysiloxane, 1-5 parts of heat-resisting fillers, 15-30 parts of fat diisocyanate and 0.009-0.1 part of platinum-containing catalysts. The silicone adhesive prepared by the preparation method has the advantages of high transparency, good heat stability at extreme temperature and high light stability, and can be used for a bonding system in a display device with large temperature change or strong ultraviolet radiation.