The invention provides a mobile phone protective shell with a fireproof structure. The mobile phone protective shell is composed of a first frame, a second frame, a third frame, a fourth frame and a bottom plate, the first frame, the second frame, the third frame and the fourth frame are arranged on the bottom plate by injection molding, the first frame, the second frame, the third frame, the fourth frame and the bottom plate form a placement space for placing a mobile phone, the bottom plate comprises a first division plate and a second division plate, a division plate gap is formed between the first division plate and the second division plate, a through hole is formed in the first division plate, the division plate gap is filled with fireproof layers, and the fireproof layers comprise afirst fireproof layer and a second fireproof layer. The mobile phone protective shell with the fireproof structure provided by the invention has the advantages of convenient use, reasonable structuredesign and the like, brings great convenience for the use of people and has great economic value and use value.