The invention discloses sponge glue, a preparation method thereof, and a sealing strip comprising the sponge glue. The sponge glue adopts raw materials in a specific ratio, and the raw materials interact with each other and act synergistically. The odor and toxicity of the sponge glue are reduced, and the tensile strength, tear strength and weather resistance of the sponge glue are improved. A nitroso-free vulcanization accelerator is used to reduce cancerogens and odor in a high temperature heating process. More importantly, china clay, light calcium carbonate and a foaming agent are added, montmorillonite and other mineral materials and sand, silt and clay in the china clay can absorb odors and harmful substances that may be generated; by use of the foaming agent, bubbles are formed in the sponge glue, so that the sponge glue has appropriate porosity, and adsorption effects of the sponge glue on the toxic and harmful substances can be improved; at the same time epdm rubber and lightcalcium carbonate both are bonded by the china clay, and vulcanized and cured in the subsequent extrusion molding process, and the tensile strength, tear strength and weather resistance of the spongeglue are improved.