The invention discloses a double-head lock hoop for an opening process of a guide wire. The double-head lock hoop comprises a first holding hoop and a second holding hoop. The first holding hoop comprises a first screw, two first half rings and two first connecting plates. A guide wire clamping channel which is in a cylindrical shape is defined between the two first half rings. The second holdinghoop comprises a second screw, two second half rings and two second connecting plates. A rod clamping channel which is in a cylindrical shape is defined between the two second half rings. The second holding hoop is provided with at least one adjusting screw. Each adjusting screw includes a head part and an adjusting stud. Each adjusting stud is matched with the second holding hoop in a threaded mode. One end of each adjusting stud is located in the rod clamping channel. The other end of each adjusting stud is fixed to the corresponding head part. Each head part is located outside of the rod clamping channel. The double-head lock hoop has the beneficial effects that the double-head lock hoop can be connected with an opening rod securely and can clamp the guide wire effectively, the adaptability for the opening rod is high, and the adjusting ability is good, and the fixing effect when the guide wire is opened can be guaranteed.