The invention creatively discloses a medical low-frequency electric pulse therapeutic instrument, which comprises a power supply module, a high-voltage generating circuit used for generating a high voltage, a pulse output circuit used for generating a pulse waveform, and a system controller. The control signal output end of the system controller is respectively connected with the control signal input end of the high-voltage generating circuit and the control signal input end of the pulse output circuit. The high-voltage output end of the high-voltage generating circuit is connected with the high-voltage power supply end of the pulse output circuit. The power supply module supplies the power to the high-voltage generating circuit, the pulse output circuit and the system controller respectively. The medical low-frequency electric pulse therapeutic instrument adopts the system controller to control the voltage value of the high-voltage generating circuit and the pulse characteristics of the pulse output circuit. Therefore, the use safety of a user is ensured. Meanwhile, the pulse characteristics can be automatically adjusted by the user according to the requirement of the user. The usage comfort of the user is enhanced.