The invention discloses a grape vine support frame with a stable structure. The grape vine support frame comprises a group of vertical supporting main racks and further comprises longitudinal steel wires and transverse steel wires, wherein the longitudinal steel wires and transverse steel wires are arranged perpendicularly to one another; the longitudinal steel wires comprise a first longitudinalsteel wire, a second longitudinal steel wire, a third longitudinal steel wire and a fourth longitudinal steel wire; heights of the first longitudinal steel wire, the second longitudinal steel wire, the third longitudinal steel wire and the fourth longitudinal steel wire away from the ground are sequentially increased; and distances of the first longitudinal steel wire, the second longitudinal steel wire, the third longitudinal steel wire and the fourth longitudinal steel wire relative to the vertical supporting main racks are sequentially increased. The support frame is unfolded and supportedin a three-dimensional manner, so that grape vine branches and grapes on the branches are uniformly distributed, the sunshine and ventilation effects are excellent, and the grape quality is improved.