The invention relates to a preparation method for a non-stick pan. The non-stick pan comprises an aluminum alloy pan body and a pan cover, wherein the pan body is formed by stamping an aluminum platewith predefined specifications by adopting a stamping molding machine; the pan body adopts a split structure; a baffle is arranged at the bottom of the pan to divide the accommodating cavity of the pan body into at least two split bodies; the pan bottom adopts a rough and uneven structure; the rough and uneven structure helps air at the pan bottom to form a series-flow; the inner surface of the pan body is coated with a layer of a water-borne non-stick coating; and the water-borne non-stick coating is further coated with a plurality of particles made from a nano-silver material or organic guanidine antibacterial material.