The invention discloses a medicine bottle. The medicine bottle comprises a bottle cap and a bottle body. The medicine bottle is characterized in that the bottle body is provided with a conic bottle opening, an inverted-conic bottle cork is arranged in the bottle opening, and an annular handle is arranged on the top of the bottle cork; and force is exerted on the annular handle, so that the bottlecork is taken out, and the height of the annular handle is lower than the height of the inner surface wall of the bottle cap after the bottle cap is mounted. The medicine bottle has the unique designof the bottle opening and the bottle cork, and is convenient to use; and force applying is easy when the bottle cork is taken out, and sealing performance is not reduced and the universality is high during being recycled.