The invention relates to a method for preparing artificial rutile by combining mechanical activating and microwave calcining. The method comprises the steps of performing mechanical activating, performing microwave calcining and the like. According to the method for preparing the artificial rutile by combining the mechanical activating and the microwave calcining, high-titanium slag is pre-treatedin a mechanical activating mode, so that Ti2O3 in an ilmenite component of the high-titanium slag can be effectively separated, and a high-temperature pre-treatment process of the high-titanium slagcan be replaced. In addition, a microwave heating mode is adopted, so that the energy consumption is low, the pollution is free, the efficiency is high, and clean production can be realized. Accordingto the method, the raw material adaptability is high; the artificial rutile with the TiO2 content of 92 percent or above by weight can be prepared.