The invention relates to ultrahard organosilicone hydrophobic glass resin which is prepared by mixing hydrogen-containing polymethylhydrosiloxane, vinyl MQ silicon resin, polyhydroxy polysiloxane, amino silicon oil and a diluent for reaction with a silane coupling agent and polyvinylsilazane under the action of a Karsted catalyst. The invention further provides a preparation method of the ultrahard organosilicone jydrophobic glass resin. The ultrahard organosilicone jydrophobic glass resin prepared according to the preparation method disclosed by the invention can realize autocatalysis for crosslinking solidification at room temperature, and a coating film is uniform, transparent and not cracked; furthermore, the ultrahard organosilicone hydrophobic glass resin is high in compactness, hydrophobicity and stain resistance; a contact angle between the coating film and water is greater than 120 degrees, and the visible light transmittance is higher than 85 percent, and the ultrahard organosilicone hydrophobic glass resin can resist a temperature being 500 DEG C or higher.