A compensation pixel circuit, a display panel, a display apparatus, a regional compensation method and a driving method are provided. The compensation pixel circuit (100) includes a compensation driving circuit (110) and a signal acquiring circuit (120) connected with the compensation driving circuit (110). The compensation driving circuit (110) includes a driving transistor and an organic light-emitting diode. The compensation driving circuit (110) is configured to receive a light-emitting data signal, compensate a threshold voltage of the driving transistor, and drive the organic light-emitting diode to illuminate in accordance with the light-emitting data signal. The signal acquiring circuit (120) is configured to acquire a gate voltage of the driving transistor. Threshold voltage compensation can be realized by collecting the gate voltage of the driving transistor in the compensation pixel circuit and compensating the surrounding non-compensation pixel circuits based on the voltage. This arrangement reduces the number of compensation driving circuits and the area on the panel occupied by the driving circuits, facilitating improvement of the resolution of the display panel.