The invention discloses a manufacturing method of liquor calabash boiled in traditional Chinese medicine. The manufacturing method comprises manufacturing of the liquor calabash and manufacturing of aliquor calabash plug. The manufacturing method of the liquor calabash comprises the steps of selecting a calabash, cutting an opening for the calabash, drawing out and removing calabash seeds and theinner membrane, carrying out first boiling, drawing out and removing the inner membrane again, carrying out first drying in the shade, carrying out second boiling, carrying out second drying in the shade, carrying out third boiling and carrying out third drying in the shade. The manufacturing method of the liquor calabash comprises the steps of drilling, fixing, sealing ring way turning and sealing ring installing. Compared with a liquor calabash manufactured with a chemical material in the market, the manufactured liquor calabash is safer to use, by means of three times of boiling in the traditional Chinese medicine, raw bitterness sent out by the inner wall of the calabash when the calabash is used for soaking water at ordinary times can be removed, pores in the inner wall of the calabash can be stuffed, the function of preventing leakage is achieved, and the mothproof function can be achieved effectively.