The invention provides a hand-operation portable seedling-raising box. The hand-operation portable seedling-raising box comprises a base, a lift-drop support, a top plate, an enclosing casing, an upper pressure disc and a lower pressure disc. The hand-operation portable seedling-raising box provided by the invention has the advantage of simple and portable structure; stacking placement of a plurality of seedling raising boxes can be easily realized; connecting assemblies are simple in structure and facilitate disassembling, assembling and integral jointing; and a plastic-film enclosing casingis arranged at the periphery of a box profile, and the thickness of the plastic-film enclosing casing can be adjusted according to usage occasions, so transparency is guaranteed, and the weight of thewhole box is reduced at the same time. The hand-operation portable seedling-raising box provided by the invention also has the advantage of convenient and simple operation; through lifting and dropping of the plastic-film enclosing casing, the sizes of an air inlet and an air outlet can be controlled; through adoption of the plastic-film enclosing casing, the cost is low, and replacement and cleaning can be easily realized; thus, the quality and efficiency of seedling raising can be improved; the labor is reduced; and the cost is saved.