The invention provides an artificial feed for adult blister beetles as well as a preparation method and application of the artificial feed, and belongs to the technical field of breeding of insects. The artificial feed comprises the following components in parts by weight: 70-75 parts of water, 5-10 parts of soybean flour, 5-10 parts of yeast powder, 5-10 parts of pollen, 4-5 parts of multi-vitamin glucose, 1-5 parts of ascorbic acid, 0.01-0.02 part of a preservative, 0.5-1.0 part of royal jelly, 0.5-1.0 part of honey and 1-3 parts of agar powder. The components are selected for making the artificial feed, so that saccharide, protein and fatty acid required for growth of the adult blister beetles are guaranteed, intake of the adult blister beetles is independent of bean flowers, and afterthe artificial feed provided by the invention is fed, normal growth and development of the adult blister beetles can be guaranteed, and the life of the adult blister beetles can also be guaranteed. The artificial feed provided by the invention and a natural feed are similar in the number of egg laying early stage days and the egg laying quantity.